You can only prevent users from modifying Exploit protection settings by using Group Policy. If you have another antivirus app installed and turned on, Microsoft Defender Antivirus will turn off automatically. (In early versions of Windows 10, Windows Security is called Windows Defender Security Center). Users will still have access to other settings in the App & browser control section, such as those settings for Windows Defender SmartScreen, unless those options have been configured separately. Important security info Windows Security is built-in to Windows and includes an antivirus program called Microsoft Defender Antivirus. The settings will be either greyed out or not appear if you enable this setting. You can prevent users from modifying settings in the Exploit protection area. Prevent users from making changes to the Exploit protection area in the App & browser control section This option can be useful if you don't want employees in your organization to see or have access to user-configured options for the features shown in the section. You can also choose to hide the section from users of the machine. IT administrators can get more information at Exploit protection. You can prevent users from modifying these specific options with Group Policy. In Windows 10, version 1709 and later, the section also provides configuration options for Exploit protection. IT administrators and IT pros can get configuration guidance from the Windows Defender SmartScreen documentation library. The App and browser control section contains information and settings for Windows Defender SmartScreen.

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